Pharmacokinetics. The absorption is independent of food intake. The bioavailability of escitalopram is approximately 80%. The mean time to maximum plasma concentration buy anavar 4 hours after repeated use. The apparent volume of distribution after oral administration is from 12 to 26 l / kg. The binding of escitalopram and its main metabolites in the plasma proteins below 80%. Escitalopram is metabolised in the liver to the demethylated and didemetilirovannogo metabolites. Both are pharmacologically active. Main ingredient and its metabolites in the form of partially allocated glucuronides.