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To determine whether oxymetholone increases lean body mass (LBM) and skeletal muscle strength in older persons, 31 men 65-80 yr of age were randomized to placebo (group 1) or 50 mg (group 2) or 100 mg (group 3) daily for 12 wk. For the three groups, total LBM increased by +/- , +/- (P < ), and +/- kg (P < ), respectively. Trunk fat decreased by +/- , +/- (P = ), and +/- kg (P = ) in groups 1, 2, and 3, respectively. Relative increases in 1-repetition maximum (1-RM) strength for biaxial chest press of +/- and +/- % in the two active treatment groups were significantly different from the change (- +/- %) for the placebo group (P < ). For lat pull-down, 1-RM changed by - +/- , +/- , and +/- % for the groups, respectively (1-way ANOVA, P = ). The pattern of changes among the groups for LBM and upper-body strength suggested that changes might be related to dose. Alanine aminotransferase increased by 72 +/- 67 U/l in group 3 (P < ), and HDL-cholesterol decreased by -19 +/- 9 and -23 +/- 18 mg/dl in groups 2 and 3, respectively (P = and P = ). Thus oxymetholone improved LBM and maximal voluntary muscle strength and decreased fat mass in older men.

This year, Studio Aandacht is running for 15 years and we have been together as a couple for 25 years. To celebrate this we treated ourselves to the newly opened Hide Out apartment in the Michelberger Hotel; The apartment consists of a big white wooden house built inside a huge loft situated in the back of the hotel. In this white house is a bedroom and top of the stairs a smaller bedroom, but we let the children stay at home in order to fully enjoy the sauna, rain shower and bathtub, and o yes on the left we also found a build-in kitchen. So you could actually hide out here if you want. In stead we went on being hero’s in Berlin…


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Before coming to Eindhoven, I studied metal craftsmanship at Ecole Boulle. This school teaches students the traditional French craft heritage. There, I learned to have a good vision in 3D, precise technical skills and an eye for quality. Some aspects of this education have remained strongly in my mind: as we were forging our own tools with a fire torch and a hammer, I designed my own tools -all laser cut in steel- to construct the ‘Regen’ garments and accessories. I also love all the little technical tricks that make crafts and techniques being so smart. And to conclude, I really enjoy the craftsman routine: spending time in an atelier, being physically active and focused, trying out different tools, making a mess, and having the greatest satisfactory feeling when all the products are finally done and the atelier is clean again.
 
What fascinates you about designing materials?

First of all I would say that I am a materialist and therefore, I like to touch and feel the matter. I like the weight, the texture and the smell of things. I feel connected to the materials because my senses can relate to them. I like the smell of Argon when I weld, the smell of sheep when I work with wool, the smell of latex when I work on ‘Regen’. All these details give an atmosphere to my days. Besides this, I am seeking unexpected outcomes from common materials. I enjoy playing with their limits, or combine them to extract possibilities they haven’t given yet. When I manage to get a surprising effect, then I feel that I have achieved my goal.
 
Can you describe your creative process?

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